div#IsiBottomTray {
position: fixed;
    transition: all 
ease 0.2s;
    z-index: 150;
    bottom: 0;
    /* max-width: 1280px; */
    width: 100%;
    background-color: #fff;
    /* padding-top: 16px;
    padding-bottom: 16px; */
    box-shadow: 0 -2px 4px #0003;}


div#fullIsi.demo-shell.demo-shell--hide-fixed-bottom div#IsiBottomTray {
    opacity: 0;
    display: none;
}

body.isi-expanded .quantum-long-form-text #closesFullIsi{
    display: block;
}
body:not(.isi-expanded) #closesFullIsi {
    display: none;
}

div#fullIsi .isi-container {
    max-width: 800px;
    margin-inline: auto;
}


div#fullIsi span.isi-font-bold {
    font-weight: bold;
  letter-spacing: 0.32px;
  color: #5b2b82;
}

div#fullIsi  p.isi-font {
    font-family: Outfit;
    font-size: 16px;
    font-weight: normal;
    font-stretch: normal;
    font-style: normal;
    line-height: 1.25;
    letter-spacing: normal;
    text-align: left;
    color: #77777a;
    margin-bottom: 16px;
}

div#fullIsi  h3.isi-heading {
    font-family: Outfit;
    font-size: 18px;
    font-weight: bold;
    font-stretch: normal;
    font-style: normal;
    line-height: 1.22;
    letter-spacing: normal;
    text-align: left;
    color: #5b2b82;
    margin-bottom: 16px;
    display: block !important;
    max-width: 800px;
    margin-inline: auto;
}


div#fullIsi p.isi-font.last-isi-font {
    margin-bottom: 20px;
}

div#fullIsi .quantum-isi-tray__content.quantum-long-form-text h3:first-child {
    display: none;
}

div#fullIsi span.isi-font-bold.text-line {
    text-decoration: underline;
}
div#fullIsi .isi-purple {
    background-color: #e6dfec;
    padding: 8px 0px;
    margin-bottom: 16px;
}

div#fullIsi .isi-purple h3.isi-heading {
    margin-bottom: 0;
}

div#fullIsi .quantum-isi-tray__content-preview.quantum-long-form-text  h5 {
    display: none;
}
div#fullIsi button#opensFullIsi {
    position: absolute;
    top: 5px;
    right: 17%;
    /* width: 20px; */
    /* height: 20px; */
    background: transparent;
    cursor: pointer;
}
div#fullIsi button#opensFullIsi span.quantum-button__text {
    display: flex;
    align-items: center;
    font-family: Outfit;
    font-size: 16px;
    font-weight: bold;
    font-stretch: normal;
    font-style: normal;
    line-height: 1.25;
    letter-spacing: 0.32px;
    text-align: left;
    color: #5b2b82;
    gap: 8px;
}

div#fullIsi button#opensFullIsi span.quantum-button__text svg {
    width: 14px;
    height: 11px;
    transform: rotate(180deg);
}

div#fullIsi button#opensFullIsi,
div#fullIsi button#opensFullIsi:focus {
    border: none !important;
outline:none;
}
/* div#fullIsi button#opensFullIsi::before{
    content: '';
    background: url('data:image/svg+xml,<svg xmlns="http://www.w3.org/2000/svg" width="19" height="14" viewBox="0 0 19 14" fill="none"><path d="M15.875 3.81818L9.375 9.81818L2.875 3.81818" stroke="%235B2B82" stroke-width="1.5" stroke-linecap="round" stroke-linejoin="round"/></svg>');
    width: 134px;
    height: 20px;
    background-size:100%;
    padding-inline: 0;
    min-width: 200px;
    background-position: bottom;
} */

.reference-container p.isi-ref{
    font-family: Outfit;
    font-size: 11px;
    font-weight: normal;
    font-stretch: normal;
    font-style: normal;
    line-height: 1.36;
    letter-spacing: normal;
    text-align: left;
    color: #77777a;
    margin-bottom: 80px;
}



.reference-container {
    max-width: 800px;
    margin-inline: auto;
}


 @media (max-width: 991px) {
    div#header .quantum-header__mobile-content button svg {
    width: 25px;
    margin-top: 5px;
}

    .reference-container p.isi-ref{
    margin-bottom: 40px;
    padding-inline:16px;
}

  div#fullIsi .quantum-isi-tray__content.quantum-long-form-text {
    padding: 20px 16px 20px;
}
div#fullIsi .quantum-isi-tray__content-preview.quantum-long-form-text .isi-container{
    padding-inline: 16px;
}

div#fullIsi button#opensFullIsi span.quantum-button__text {
    color: transparent;
}

div#fullIsi button#opensFullIsi {
    right: 10px;
    top: 20px;
}

div#fullIsi button#opensFullIsi span.quantum-button__text svg {
    width: 20px;
    height: 20px;
    transform: none;
}
div#fullIsi .isi-purple h3.isi-heading {
    margin-bottom: 0;
    max-width: 250px;
    margin-inline: 0;
    padding-inline: 16px;
}
.isi-expanded .quantum-isi-tray__content.quantum-long-form-text {
    padding-inline: 0 !important;
}

.isi-expanded .isi-overlay h3.isi-heading {
    padding-inline: 16px;
    max-width: 250px !important;
    margin-inline: 0 !important;
}

.isi-expanded .isi-container {
    padding-inline: 20px;
}

.isi-expanded button#closesFullIsi {
    right: 10px !important;
    top: 20px !important;
}
body.isi-expanded .component.container:nth-of-type(5) {
    display: none;
}

.isi-expanded div#fullIsi {
    margin-top: 0 !important;
}
div#header .quantum-header__mobile-content button svg {
    width: 25px;
    margin-top: 5px;
}
 }
 @media (min-width: 991px) {
div#fullIsi .quantum-isi-tray__content.quantum-long-form-text {
    padding: 80px 0px 0px;
}
 }


 .isi-expanded .quantum-isi-tray__content-preview.quantum-long-form-text {
    display: none;
}

.isi-expanded div#fullIsi{
    z-index: 1000;
    width: 100%;
    /* top: 11%; */
    position: relative;
    /* margin-top: -20%; */
    background: #fff;
}

.isi-expanded div#fullIsi .quantum-isi-tray__content.quantum-long-form-text {
    padding-top: 0  !important;
}

.isi-expanded button#closesFullIsi {
    position: absolute;
    top: 7px;
    right: 17%;
    /* width: 20px; */
    /* height: 20px; */
    background: transparent;
    cursor: pointer;
    border: none;
    outline: none;
}




.isi-expanded .isi-overlay {
    background-color: #e6dfec;
    padding: 8px 0px;
    margin-bottom: 16px;
}

.isi-expanded .isi-overlay h3.isi-heading {
    margin-bottom: 0 !important;
}

div#fullIsi span.isi-font-bold .isi-pi-text {
    font-weight: bold;
    letter-spacing: 0.32px;
    color: #5b2b82;
    font-family: Outfit;
    font-size: 16px;
    font-stretch: normal;
    font-style: normal;
    line-height: 1.25;
    letter-spacing: normal;
    text-align: left;
    text-decoration: underline;
}


div#header li.quantum-drop-down-menu__list-item .quantum-drop-down-menu__link:hover {
    color: #e16a2d !important;
    text-decoration: none;
}

header.header-nav .component.container > .component-content a.quantum-top-nav__link{
    text-decoration: none;
}
footer#footer a.quantum-link.quantum-footer__link:hover{
        color: #e16a2d !important;

}

.isi-expanded div#clinical-data-promo-horizontal {
    display: none !important;
}



 @media (max-width: 1320px) and (min-width: 991px)  {
    header.header-nav .component.container > .component-content .row.component.column-splitter {
    padding-left: 16px;
}
 }